Laryngeal granulomas: A rare clinical entity requiring etiology-specific management – A retrospective study of 16 cases

Multifactorial etiology of laryngeal granulomas range from intubation trauma, gastroesophageal reflux, voice abuse, or infection. They are associated with diagnostic and therapeutic challenges, with a notable tendency for recurrence. Present. study was done to evaluate the clinical presentation, etiological factors, treatment outcomes, and recurrence patterns of laryngeal granulomas in a retrospective cohort of 16 patients, with emphasis on etiology-specific management strategies. Data on demographics, clinical features, videolaryngoscopic findings, and treatments were analyzed. Management approaches, including proton pump inhibitors, systemic or intralesional corticosteroids, voice therapy, and surgical excision, were tailored based on the underlying etiology. Follow-up assessments were performed at regular intervals to monitor treatment response and recurrence. Videolaryngoscopy showed laryngopharyngeal reflux in 37.5%. Systemic steroids (68.75%) and antireflux therapy (37.5%) were the main treatments. Granuloma size reduction was noted in 68.75% of cases, with 12.5% showing no recurrence. Reflux-related granulomas responded well to conservative therapy, while postintubation lesions required surgical intervention with intralesional steroids.