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September 28, 2025ANZ Journal of Surgery

Non‐Tuberculous Laryngeal Granulomas: Systematic Review and Case Series

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Authors

SKSeraphina KeyMLMichael Fook‐Ho LeeWJWilliam Jiang

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Overview

Systematic review highlights diverse causes of laryngeal granulomas in 30 patients, indicating the need for precise diagnostic processes.

Key Points

  • Autoimmune and infectious causes of laryngeal granulomas require a high index of suspicion for effective management.
  • Out of 2621 studies, nine papers involving 30 patients were reviewed to identify relevant cases and causes.
  • The systematic review assessed histological examination findings, revealing diverse non-malignant aetiologies.
  • Case series indicated the necessity for repeat biopsies when initial findings are inconclusive or non-diagnostic.

Cite This Study

Key et al. (2025) studied this question.

synapsesocial.com/papers/68d909fc41e1c178a14f5d30https://doi.org/10.1111/ans.70327
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Laryngeal granulomas (literature review)2025
  2. 2Laryngeal granulomas: A rare clinical entity requiring etiology-specific management – A retrospective study of 16 cases2025
  3. 3Isolated laryngeal tuberculosis complex infection: expect the unexpected2024
  4. 4C40-35 Extensive Pulmonary Granulomas: A Case Without a Culprit2026
  5. 5Granulomatous inflammation in histopathological samples: examining the aetiological spectrum, diagnostic challenges, and future perspectives2026