Case report details tramadol use disorder and successful methadone therapy in a patient, highlighting opioid substitution needs.
Tramadol is a centrally acting analgesic which is easily available and widely prescribed for pain hence subjected for misuse, dependence and addiction. This case report presents a 32-year-old Tanzanian female who developed tramadol use disorder following prolonged self-medication for primary dysmenorrhea over past 12 years. She progressed from intermittent use to daily dependence on high doses of tramadol, culminating in significant socio-occupational dysfunction. She was successfully managed with methadone maintenance therapy, highlighting the need for awareness, early intervention, and access to opioid substitution therapy.
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Mbughi et al. (2025) studied this question.
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