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September 10, 2025

Development and Validation of RP HPLC Method for the Simultaneous Estimation of repaglinide and Metformin HCL Tablet Formulation

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New assay method shows accuracy in estimating Repaglinide and Metformin HCL in formulations, suggesting quality control potential.

The developed RP HPLC method enabled simultaneous estimation of repaglinide and metformin HCL.
Linearity was confirmed with R2 values of 0.9960 for repaglinide and 0.9974 for metformin HCL.
The method demonstrated robustness and specificity for quality control in pharmaceutical formulations.
Accurate estimations were achieved over specified concentration ranges for both drugs.

Patil et al. (2025) studied this question.

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