This in vitro study compares remineralization effects of fluoridated and non-fluoridated toothpastes on dental caries, indicating the effectiveness of nano hydroxyapatite.
Dental caries is a global concern marked by enamel demineralization due to bacterial activity. This in vitro study compared the remineralization efficacy of fluoridated and non-fluoridated dentifrices. Fifty demineralized premolars were divided into five groups and treated for 30 days. Nano hydroxyapatite demonstrated the highest surface microhardness improvement, followed by sodium fluoride, calcium sucrose phosphate and EnamelMax. All tested agents showed remineralizing potential, with nano-hydroxyapatite being the most effective.
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Batha et al. (2025) studied this question.
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