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September 10, 2025Frontiers in EndocrinologyOpen Access

Clinicopathological features and outcomes in patients with concurrent medullary and papillary thyroid carcinoma

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Authors

RSRuonan SunXLXueting LiuJLJiabin Liu

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Overview

Analysis shows similar clinicopathological features and prognosis in patients with medullary and papillary thyroid carcinoma, highlighting key tumor characteristics.

Key Points

  • Patients with concurrent medullary thyroid carcinoma and papillary thyroid carcinoma showed similar clinicopathological features as those with medullary thyroid carcinoma alone.
  • Recurrence rates were comparable between the combination group and the MTC group, with no significant differences in invasiveness.
  • Analysis identified max tumor diameter and capsule invasion as significant prognostic factors associated with structural abnormalities in the MTC group.
  • The study highlights the importance of understanding combined tumor presentations in thyroid cancer for better patient management.

Cite This Study

Sun et al. (2025) studied this question.

synapsesocial.com/papers/68c1c31254b1d3bfb60f073fhttps://doi.org/10.3389/fendo.2025.1625989
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Analysis of the concurrent occurrence of medullary thyroid carcinoma and papillary thyroid carcinoma: A dual center, retrospective study in China.2026
  2. 2Clinicopathological and follow-up features of coexisting medullary and papillary thyroid cancer2026
  3. 3A Malignant Duo: Mixed Medullary and Follicular Variant Papillary Thyroid Cancer2024 · 2 citations
  4. 4Simultaneous occurrence of papillary thyroid carcinoma, medullary thyroid carcinoma, and lymphoma: A case report2024 · 2 citations
  5. 5Simultaneous Medullary and Papillary Thyroid Carcinomas: Personal Experience Report and Literature Review2025 · 3 citations