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September 10, 2025ScientificaOpen Access

In Vivo Antibacterial and Biochemical Effects of Moringa oleifera Leaf Extract in a Rat Model of Multidrug‐Resistant Salmonella Typhimurium

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Authors

MNMegane Nkemendong NkamkeuWLWoquan Sama LumaLALaupy Anne Awah

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Overview

In vivo analysis shows Moringa oleifera significantly reduces bacterial load in rats infected with multidrug-resistant Salmonella, suggesting its potential therapeutic role.

Key Points

  • The extract of Moringa oleifera demonstrated high antibacterial activity against multidrug-resistant Salmonella.
  • A significant reduction in fecal bacterial colonies was observed across all treatment doses compared to the control group.
  • The study utilized a rat model to evaluate in vivo effects of the methanol extract over ten days of treatment.
  • No adverse effects were noted, supporting the safety of Moringa oleifera as a potential alternative treatment.

Cite This Study

Nkamkeu et al. (2025) studied this question.

synapsesocial.com/papers/68c1c32e54b1d3bfb60f13c2https://doi.org/10.1155/sci5/5377172
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Antibacterial activity against multidrug-resistant Salmonella, toxicity and biochemical effects of Moringa oleifera leaf extracts in mice2024 · 1 citations
  2. 2Antibacterial Potential of Moringa oleifera Extracts against MDR Enterobacteriaceae from Hospitalized Patients in Mardan, Pakistan2025
  3. 3Exploitation of Phytochemical Extracts of Moringa oleifera as Antimicrobial Agent against Human Pathogenic Bacteria2024 · 1 citations
  4. 4The Antibiotic Potential of Moringa oleifera Leaf on Staphylococcus aureus2025
  5. 5Comparative Phytochemical Characterization and Antibacterial Activity of Ethanol and Aqueous Extracts of Moringa peregrina and Moringa oleifera against Multidrug-Resistant Bacteria2026