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June 11, 2026ScientificaOpen Access

Current Therapeutic Strategies, Recent Advances and the Emerging Potential of Natural Products in Hepatocellular Carcinoma

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Authors

FMFelix Wambua MuemaCMCatherine MillerLHLionel Hebbard

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Overview

This review examines current therapies for HCC and highlights natural products' potential in improving treatment outcomes.

Key Points

  • The aim is to evaluate current HCC treatments and explore the potential of natural products in therapy.
  • Review of current HCC treatment modalities and their limitations.
  • Analysis of the pharmacological activities of plant-derived phytochemicals.
  • Discussion on nanotechnology-based drug delivery systems to enhance treatment efficacy.
  • Natural products induce apoptosis and inhibit key signaling pathways (PI3K/Akt, MAPK, NF-κB).
  • Nanotechnology improves solubility and selectivity of phytochemicals in cancer therapeutics.
  • The integration of phytochemicals and nanomedicine shows promise for overcoming treatment barriers.

Cite This Study

Muema et al. (2026) studied this question.

synapsesocial.com/papers/6a2a51d780c8f91e7f39e00ehttps://doi.org/10.1155/sci5/3431270
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Herbal-derived phytochemicals in hepatocellular carcinoma: A review of molecular targets and tumor microenvironment interventions2026
  2. 2Natural Products and Traditional Chinese Medicine in Hepatocellular Carcinoma: From Pharmacological Mechanisms to Clinical Translation2026
  3. 3Breaking Down the Arsenal: Recent Progress in the Nanotherapeutic Strategies for Hepatocellular Carcinoma Treatment2024 · 1 citations
  4. 4The role of medicinal plants in the management of hepatocellular carcinoma and its metastasis2025
  5. 5Plant-derived natural products against hepatocellular carcinoma: chemical diversity, mechanisms of action, and organ-based classification2026