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September 10, 2025Journal of Medical and Health SciencesOpen Access

Hypoglycemic and Hypolipidemic Effects of Tithonia diversifolia Aqueous Root Extract in Western Diet-Fed Wistar Albino Rats

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Authors

DODamaris Akinyi OkunaMoi University

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Implication

This study demonstrates hypoglycemic and hypolipidemic effects of Tithonia diversifolia in rats, suggesting it may compete with atorvastatin and glibenclamide.

Key Points

  • Extract treatment significantly reduced fasting glucose and cholesterol levels, indicating its hypoglycemic effects.
  • When compared to atorvastatin, the extract at 400 mg/kg achieved comparable reductions in fasting glucose levels.
  • Wistar rats fed a Western diet exhibited increased fasting blood glucose, confirming diet-related metabolic disturbances.
  • Further research is needed to isolate bioactive compounds from Tithonia diversifolia for potential therapeutic applications.

Cite This Study

Damaris Akinyi Okuna (2025) studied this question.

synapsesocial.com/papers/68c1c62654b1d3bfb60f182chttps://doi.org/10.51317/ecjrmhs.v5i1.577
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Computation and Experimental Approaches to Uncover the Antidiabetic Potential of Insulin Leaf (Tithonia diversifolia) Extract Based on Flavonoid Constituents2026
  2. 2Effects of Ethanolic Leaf Extract of Telfairia Occidentalis on an Alloxan Induced Diabetic Male Wistar Rats2025
  3. 3Antihyperlipidemic Activity of Tamarind (Tamarindus indica) Extract on the Lipid Profile of Albino Rats2024
  4. 4Phytochemical and Pharmacological Evaluation of Wodyetia Bifurcata Leaf Extracts in High-Fat-Diet-Induced Hypercholesterolemia-Associated Diabetes in Albino Rats2026
  5. 5Hypolipidemic and anti-atherosclerogenic effect of Glycyrrhiza glabra root extract in high fat diet induced hypercholesterolemic rats2025