Darier-Ferrand Dermatofibrosarcoma Protuberans: A Rare Soft Tissue Tumor Of The Breast And A Review Of The Literature

In cases where a mass in the breast is diagnosed and a tru-cut or excisional biopsy is performed, mesenchymal lesions are rarely encountered. Dermatofibrosarcoma protuberans is a rare mesenchymal tumour originating from the dermis in clinical practice. It is generally a low-grade sarcoma and rarely metastasizes. Other malignant mesenchymal lesions observed in the breast include leiomyosarcoma, liposarcoma, chondrosarcoma, malignant fibrous histiocytoma, rhabdomyosarcoma, spindle cell mesenchymal tumour, and angiosarcoma. Primary mesenchymal tumours of the breast make up less than 1% of all breast malignancies. In this report, a 38-year-old female patient with a painless mass measuring approximately 7x6 cm, protruding from the upper inner quadrant of the right breast, was presented. The tru-cut biopsy performed on the lesion revealed a spindle cell mesenchymal tumour. A PET-CT scan showed a mass with increased SUV-max in the right breast and reactive lymph nodes in the right axilla. No distant metastasis was observed. The patient underwent a wide local excision with a 1 cm clear surgical margin. She was discharged on the 2nd postoperative day without complications. The pathology result of the main specimen was dermatofibrosarcoma protuberans, with negative surgical margins, and the patient was placed under clinical and radiological follow-up.