Key result
Surgical excision with adequate margins successfully treats rare breast dermatofibrosarcoma protuberans without one-year recurrence.
Why the study?
Dermatofibrosarcoma protuberans is a rare soft tissue neoplasm with extremely uncommon breast location, often confused with other primary breast lesions.
Case Report (n=1)
Highlights the rare presentation of dermatofibrosarcoma protuberans in the breast and the importance of adequate surgical resection margins.
Supports margin-negative excision for rare breast DFSP; leaves open generalizability and optimal long-term protocols.
INTRODUCTION: Dermatofibrosarcoma protuberans is a rare neoplasm of soft tissues and its location in the breast is extremely uncommon. Confusion is possible with other primary breast lesions. CASE PRESENTATION: A 75-year-old Caucasian woman presented with a mass in her left breast 21 years after being diagnosed with invasive ductal carcinoma of the right breast, treated by a right mastectomy and axillary dissection followed by radiotherapy and breast reconstruction. Mammography revealed a dish-shaped skin nodule formation in the upper outer quadrant of her left breast. Echography confirmed the presence of a lesion measuring 1.4 × 0.8 cm. Based on imaging, the diagnosis was a probable angiosarcoma. Due to the presence of a pacemaker for cardiac arrhythmia and full anticoagulation therapy for a pulmonary embolism, magnetic resonance imaging and a biopsy were not done. We proceeded directly to a quadrantectomy and the final diagnosis revealed a dermatofibrosarcoma protuberans, 1. 8 cm in its greatest microscopic dimension, located 0.1 cm from the upper surgical margin. To ensure the wide resection margins required for this type of neoplasm, a re-excision was performed. CONCLUSION: A dermatofibrosarcoma protuberans of the breast is an uncommon discovery. The aim of this case report is to highlight the importance of the surgical procedure in cases of the discovery of dermatofibrosarcoma protuberans. Re-excision may be necessary to ensure adequate resection margins.
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Cottier et al. (2011) conducted a case report in Dermatofibrosarcoma protuberans of the breast (n=1). Quadrantectomy and re-excision was evaluated on Recurrence. Surgical excision with adequate resection margins successfully treated a rare dermatofibrosarcoma protuberans of the breast, with no evidence of recurrence at one year.
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