What type of study is this?

This is a Systematic Review study (also classified as: Meta-Analysis).

September 10, 2025Dermatologic TherapyOpen Access

Comparisons of Efficacy and Safety of Different Doses of Doxycycline for the Treatment of Moderate‐to‐Severe Acne Vulgaris: A Systematic Review and Network Meta‐Analysis

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Systematic review assesses efficacy and safety of doxycycline doses for acne vulgaris, suggesting 40 mg/day may reduce lesions.

40 mg/d of doxycycline effectively reduces inflammatory acne lesions compared to placebo, p = 0.03.
Participants aged 12–60 were included across four RCTs verifying the 40 mg/d dosage against various higher doses.
Network meta-analysis utilized to analyze efficacy, safety, and adverse events linked to different doxycycline doses.
Findings indicate 40 mg/d of doxycycline may offer a favorable safety profile relative to higher doses.

Shang et al. (2025) studied this question.

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September 10, 2025Dermatologic TherapyOpen Access

View Full Paper

Ask AI

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Authors

Systematic review assesses efficacy and safety of doxycycline doses for acne vulgaris, suggesting 40 mg/day may reduce lesions.

40 mg/d of doxycycline effectively reduces inflammatory acne lesions compared to placebo, p = 0.03.
Participants aged 12–60 were included across four RCTs verifying the 40 mg/d dosage against various higher doses.
Network meta-analysis utilized to analyze efficacy, safety, and adverse events linked to different doxycycline doses.
Findings indicate 40 mg/d of doxycycline may offer a favorable safety profile relative to higher doses.

Shang et al. (2025) studied this question.

View Full Paper

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Bookmark