What type of study is this?

September 10, 2025PLoS ONEOpen Access

Circulating angiotensin-converting enzyme 2 concentration is associated with acute kidney injury and mortality in sepsis

View Full Paper

Ask AI

Bookmark

Authors

CCChing-En ChenNational Yang Ming Chiao Tung University RCRuey‐Hsing ChouNational Yang Ming Chiao Tung University JGJiun‐Yu GuoNational Yang Ming Chiao Tung University

Discussion

Member takes

Implication

Observational analysis shows higher ACE2 concentrations correlate with increased AKI and ICU mortality in sepsis patients, suggesting potential prognostic value.

Key Points

Higher circulating ACE2 levels are linked to increased risk of acute kidney injury in sepsis patients.
Patients with high ACE2 concentrations showed a significantly reduced survival rate, emphasizing its role in critical illness outcomes.
Increased ACE2 levels correlate negatively with hemoglobin levels, indicating a complex interplay with sepsis physiology.
ACE2 elevation serves as an independent predictor of ICU mortality, highlighting its potential as a prognostic biomarker.

Cite This Study

Chen et al. (2025) studied this question.

synapsesocial.com/papers/68c1d7fe54b1d3bfb60fa748 https://doi.org/10.1371/journal.pone.0330668

View Full Paper

Ask AI

Bookmark

Implication

Observational analysis shows higher ACE2 concentrations correlate with increased AKI and ICU mortality in sepsis patients, suggesting potential prognostic value.

Circulating angiotensin-converting enzyme 2 concentration is associated with acute kidney injury and mortality in sepsis

Discussion

Member takes

Implication

Key Points

Cite This Study

Circulating angiotensin-converting enzyme 2 concentration is associated with acute kidney injury and mortality in sepsis

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider