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September 10, 2025Annals of Pediatric CardiologyOpen Access

Forewarned is forearmed: The critical role of prenatal diagnosis in managing high-risk neonates with transposition of great arteries-intact ventricular septum

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Authors

NYNaimisha YenduriBVBalu VaidyanathanSKSonia Karapurkar

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Overview

Case reports reveal prenatal diagnosis informs critical interventions for cyanosis in neonates with TGA-IVS.

Key Points

  • Severe hypoxemia after birth can occur in neonates with transposition of great arteries-intact ventricular septum.
  • Restrictive foramen ovale or ductus arteriosus can significantly increase risks of mortality after birth.
  • Emergency interventions like balloon atrial septostomy and ductal stenting highlight prenatal diagnosis importance.
  • Identification of high-risk features before birth can lead to timely management decisions for affected neonates.

Cite This Study

Yenduri et al. (2025) studied this question.

synapsesocial.com/papers/68c1dd9254b1d3bfb60fbff4https://doi.org/10.4103/apc.apc_21_25
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prenatal Features of Ductus Arteriosus Constriction and Restrictive Foramen Ovale in d-Transposition of the Great Arteries1999 · 178 citations
  2. 2Prenatal diagnosis of transposition of the great arteries over a 20-year period: improved but imperfect2014 · 72 citations
  3. 3Fetal-to-Neonatal Transition of an Infant with Transposition of the Great Arteries and Intact Ventricular Septum: A Case Report2024 · 2 citations
  4. 4Transposition of the great arteries: from fetus to adult2008 · 36 citations
  5. 5Detection of Transposition of the Great Arteries in Fetuses Reduces Neonatal Morbidity and Mortality1999 · 772 citations