Key result
Prenatal echocardiographic identification of both a diminutive ductus arteriosus and abnormal foramen ovale in fetuses with TGA was associated with immediate neonatal death (2 of 2 cases).
Why the study?
Does prenatal echocardiography identify fetuses with d-transposition of the great arteries at high risk for postnatal hypoxemia and death?
Population
16 fetuses with d-transposition of the great arteries with intact ventricular septum or small ventricular…
Design
Cohort
Follow-up
early neonatal period
Authors
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May flag high-risk TGA fetuses for specialized delivery planning; hypothesis-generating and requires validation in larger cohorts.
Observational (n=16)
Does prenatal echocardiography identify fetuses with d-transposition of the great arteries at high risk for postnatal hypoxemia and death?
Prenatal echocardiographic identification of restrictive foramen ovale and ductus arteriosus constriction in fetuses with TGA is associated with high risk for postnatal hypoxemia and early neonatal death.
Maeno et al. (1999) conducted an observational in d-transposition of the great arteries (TGA) (n=16). Abnormal features of the foramen ovale and ductus arteriosus was evaluated on Postnatal hypoxemia, restrictive foramen ovale at birth, and neonatal death. Prenatal echocardiographic identification of both a diminutive ductus arteriosus and abnormal foramen ovale in fetuses with TGA was associated with immediate neonatal death (2 of 2 cases).
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