Platelet/Mpv and Neutrophil/Lymphocyte Ratio in Prediction of Three Vascular Disease and Bypass in Patients with Acute Coronary Artery Syndrome

Acute coronary syndrome (ACS) is the most important reason for admission to the emergency department all over the world. It was aimed to evaluate the effects of Platelet/Mean Platelate Volume ratio (PMR) and Neutrophil/lymphocyte ratio (NLR) levels in terms of complications after ACS, triple vessel disease (TVD), bypass and mortality. This cross-sectional cohort study included 913 patients over the age of 18, who were admitted to the emergency department with a pre-diagnosis of ACS and admitted to the clinic between January 2013 and December 2017. Three groups were formed according to the patients' ACS diagnoses. These groups were compared in terms of PMR and NLR values, bypass, TVD and mortality. The mean age of 913 patients included in the study was 63.84±12.18 years and 346 (37.9%) were female. NLR of the patients was 3.81±4.26% and PMR was 31.0±8.63% (p=0.001). By-pass was presebt in 46 (33.1%) and TVD in 90 (64.7%) patients, both of which were most common in the NSTEMI group (p=0.001). Mortality was observed in 20 (14.4%) NSTEMI cases and 37 (9.9%) STEMI cases (p=0.001). The most common complication after ACS was ischemic heart failure (p=0.001). Gensini score of patients who underwent bypass was 70.11±56.96 points, left ventricular ejection fraction was 45.82±11.34%, NLR was 8.46±7.76%, and PMR was 35.74±2.70%, which was significantly higher than those without bypass (p=0.001). In the TVD group, NLR was 6.01±5.33% and PMR was 37.06±5.11%. It was found to be significantly higher than the group without TVD (p=0.001). In patients with acute coronary syndrome, PMR and NLR values ​​are fast, easy to apply, inexpensive and reliable laboratory tests in predicting bypass, triple-vessel disease and mortality.