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September 16, 2025

Identification of chemical composition and prediction of in vitro anti-inflammatory activity mechanism of ethyl acetate fraction of

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Authors

YWYurong WangXFXiaoyu FuSXShuyu Xu

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Overview

This study reveals anti-inflammatory effects of ethyl acetate extract in Lagenaria siceraria seeds, suggesting key compounds target inflammation pathways.

Key Points

  • High-dose ethyl acetate extract significantly suppressed inflammation in RAW 264.7 cells, showcasing its potential as an anti-inflammatory agent.
  • Key compounds like quercetin and kaempferol were identified as active components impacting inflammation pathways early in the study.
  • The approach integrated LC-MS and network pharmacology, enhancing understanding of how specific compounds exert their effects.
  • Findings support exploration of ethyl acetate's potential therapeutic applications for inflammatory conditions.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68c93fee01120bef803bb2c1https://doi.org/10.1080/14786419.2025.2559767
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