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September 30, 2025Chemistry & Biodiversity

Uncovering Anti‐Inflammatory Mechanisms of Elaeagnus angustifolia Extract via Metabolomic and Phytochemical Analyses

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Authors

AIAmer ImraishMSMehdi SeifLDLina A. Dahabiyeh

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Overview

This study demonstrates anti-inflammatory effects of Elaeagnus angustifolia extract, revealing metabolic alterations in macrophage cells, suggesting therapeutic potential.

Key Points

  • The extract significantly alters cellular metabolism, modulating inflammation-related pathways.
  • Metabolomic analysis revealed 156 differential metabolites linked to anti-inflammatory mechanisms.
  • Phytochemical profiling identified key compounds like quercetin and oleic acid crucial for biological activity.
  • The study highlights the potential of metabolomics in discovering bioactive compounds for therapeutic applications.

Cite This Study

Imraish et al. (2025) studied this question.

synapsesocial.com/papers/68dc1e3f8a7d58c25ebb202ehttps://doi.org/10.1002/cbdv.202502170
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  4. 4Phytochemistry and In Vitro Bioactivities of Elaeagnus angustifolia L. Leaves: Influence of Solvent Polarity, Antioxidant Properties, and α-Amylase Inhibition2026 · 4 citations
  5. 5Identification of chemical composition and prediction of in vitro anti-inflammatory activity mechanism of ethyl acetate fraction of 2025