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March 7, 2026MoleculesOpen Access

Phytochemistry and In Vitro Bioactivities of Elaeagnus angustifolia L. Leaves: Influence of Solvent Polarity, Antioxidant Properties, and α-Amylase Inhibition

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Authors

RBRayene BouaitaRDRanda DjemilSBSamira Bouhalit

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Overview

Investigates the antioxidant properties and α-amylase inhibition in a plant, suggesting its potential as a natural antidiabetic agent.

Key Points

  • To evaluate the impact of solvent polarity on the extraction yield and bioactivities of Elaeagnus angustifolia leaves.
  • Examined extraction yields using different solvents with varying polarity.
  • Analyzed phytochemical composition of extracts using HPLC.
  • Conducted antioxidant assays (DPPH, ABTS, FRAP) to assess activity.
  • Tested α-amylase inhibition of extracts and compared with acarbose.
  • Hydroethanolic extract yielded the highest extraction rate at 18.00%.
  • N-hexane showed the least yield at 0.05%.
  • Polar extracts demonstrated strong antioxidant activity.
  • N-hexane extract had the highest α-amylase inhibition (IC50 = 36.70 µg/mL), outperforming acarbose (IC50 = 126.14 µg/mL).

Cite This Study

Bouaita et al. (2026) studied this question.

synapsesocial.com/papers/69abc2455af8044f7a4ebbdahttps://doi.org/10.3390/molecules31050861
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