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September 12, 2025

A 30-year study of 355 cases with adult-type ovarian granulosa cell tumors in a tertiary center: Clinical features and factors predicting recurrence

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Authors

JGJingwen GanChinese Academy of Medical Sciences & Peking Union Medical CollegeXMXiao MaZhejiang A & F UniversityYCYing CaoBeijing Great Wall Hospital

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Implication

Retrospective study evaluates recurrence in adult granulosa cell tumors, highlighting prognostic factors like tumor size and FIGO stages.

Key Points

  • Recurrence occurred in 28.4% of patients, highlighting significant risk in adult granulosa cell tumors.
  • 5-year disease-free survival rate was 86.2%, while 10-year overall survival reached 97.5%, reflecting favorable outcomes.
  • Multivariate analysis revealed tumor size, FIGO stages, and surgical approach as key predictors of disease-free survival.
  • Intensified surveillance is suggested for patients with FIGO stage IC due to higher risk of recurrence.

Cite This Study

Gan et al. (2025) studied this question.

synapsesocial.com/papers/68d44a4731b076d99fa53d77https://doi.org/10.21203/rs.3.rs-7329250/v1
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