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September 12, 2025Open Access

Could the load of carbapenemase genes in hospital wastewater be a proxy for the epidemiology of emerging resistance to carbapenems in humans?

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Authors

CFC. FavierMTMylène ToubianaIZIsabelle Zorgniotti

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Overview

This study demonstrates wastewater surveillance for monitoring carbapenem resistance, suggesting its significance in infection control.

Key Points

  • Monitoring carbapenemase genes in wastewater can signal emerging AMR trends in hospital settings.
  • Emerging AMR genes were present at low levels compared to established ones, indicating infection patterns.
  • This research utilized qPCR and dPCR methods to quantify AMR genes in wastewater samples from two hospital buildings.
  • Addressing the obstacles identified will be vital for integrating wastewater monitoring into routine hospital practices.

Cite This Study

Favier et al. (2025) studied this question.

synapsesocial.com/papers/68d44c4631b076d99fa55b7fhttps://doi.org/10.1101/2025.09.01.25334728
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