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September 12, 2025Analytical Chemistry

Micelle-Confined Co–N Coordination Enables Size-Tailored Nanoemitters for High-Performance ECL Biosensing

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Authors

YDYuxuan DaiYLYixuan LiJCJérôme Chauvin

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Overview

This approach leverages micelle confinement to optimize ECL performance in biosensing, highlighting robust detection of NT-proBNP.

Key Points

  • Enhancing ECL performance through size-tailored Co-N nanoemitters significantly amplifies biomarker detection sensitivity.
  • The constructed biosensor enables selective detection of NT-proBNP with a low detection limit of 0.03 pg mL-1 in a wide dynamic range.
  • Utilizing micelle confinement principles, the spatial structure increases reactive oxygen species generation, improving ECL emission.
  • This platform may facilitate early heart failure diagnoses, indicating potential advancements in electroactive nanomaterials.

Cite This Study

Dai et al. (2025) studied this question.

synapsesocial.com/papers/68d44c5531b076d99fa560b8https://doi.org/10.1021/acs.analchem.5c04336
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