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September 16, 2025European PsychiatryOpen Access

Behavioral stabilization through low-dose Clozapine in a youth justice center.

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Case study reports improvements in aggression and conduct disturbances in youth justice center, suggesting clozapine's viability.

Improvements in conduct regulation and emotional distress were documented with low-dose clozapine administration, stabilizing the patient's behavior.
The introduction of clozapine up to 150 mg/day showed clear benefits in reducing anxiety and enhancing adaptability in a structured setting.
Following a treatment interruption, relapse occurred, demonstrating clozapine's crucial role in maintaining symptom stability during treatment.
This case highlights clozapine's potential for improving outcomes in adolescents with ASD and comorbid conduct disturbances in youth justice environments.

Vázquez et al. (2025) studied this question.

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