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Infection-associated hemophagocytic lymphohistiocytosis: A comprehensive review

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Hemophagocytic lymphohistiocytosis is a rare but fatal syndrome characterized by hyperinflammatory responses.
Diagnosis relies on clinical features like prolonged fever and elevated laboratory markers such as ferritin.
Timely recognition is crucial, as untreated hemophagocytic lymphohistiocytosis leads to high mortality rates.
Management typically involves treating underlying infections alongside potential immunosuppressive therapies.

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This review uncovers the clinical presentation of hemophagocytic lymphohistiocytosis and its diagnostic challenges.

Manisha et al. (2025) studied this question.

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