Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 17, 2025Journal of Pharmaceutical And SciencesOpen Access

Bioactivity and Health Effect of Black Garlic on Hydroxy Methylglutaryl-CoA Reductase Enzyme Activity in Male Obese Rattus Norvegicus Strain Wistar

View Full Paper
Ask AI
Bookmark
Share

Authors

IIIbrahim IbrahimEYEti YerizelEEEndrinaldi Endrinaldi

Discussion

Loading...

Member takes

Overview

Experimental study reveals that black garlic significantly lowers HMG-CoA reductase activity in obese rats, indicating potential for dyslipidemia management.

Key Points

  • Black garlic significantly decreased HMG-CoA reductase activity in rats fed a high-fat diet, supporting its therapeutic benefits.
  • The average HMG-CoA levels showed a significant difference among control and treatment groups, with a p-value of 0.004.
  • This experimental study involved 25 male Wistar rats divided into control and treatment groups receiving varying doses of black garlic.
  • The findings suggest black garlic as a promising natural agent for managing dyslipidemia in obese individuals.

Cite This Study

Ibrahim et al. (2025) studied this question.

synapsesocial.com/papers/68d4596631b076d99fa5c158https://doi.org/10.36490/journal-jps.com.v8i3.1039
View Full Paper
Ask AI
Bookmark
Share