Analysis reveals minimal volumetric differences in brain structure between upright and supine positions, suggesting stability in posture-related impacts.
Motivation: This study aims to examine the clinical implications of postural effects on brain structure. Goal(s): To investigate volumetric differences between upright and supine positions, providing a foundation for future research on how posture affects brain structure. Approach: Thirty-two healthy volunteers were scanned using a cryogen-free 1.5T MRI scanner in supine and upright postures. The 3D T1-MP-RAGE brain images were segmented into 109 regions, and their corresponding volume changes were further evaluated. Results: Most brain regions showed minimal volume change within a ±5% range, indicating structural stability across different postures. These findings provide a basis for future exploration of posture-related impacts on brain structure. Impact: These findings on posture-related brain volume stability may inform future research on the clinical implications of postural effects, enhancing our understanding of brain structure integrity across different positions.
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Ke et al. (2025) studied this question.
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