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September 17, 2025Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition

Engineered Biomimetic Iron Oxide Nanoparticles for Early MR Diagnosis and Intervention of Atherosclerotic Vulnerable Plaques

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Authors

YWYujie WangQZqianru zhouXZXiance Zhao

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Overview

In vitro and in vivo analysis reveals a novel contrast agent targeting atherosclerotic plaques, suggesting improved diagnostic specificity.

Key Points

  • The newly developed contrast agent effectively targets vulnerable atherosclerotic plaques, enhancing MRI detection capabilities.
  • In vivo studies demonstrated high signal-to-noise ratios on T2-weighted imaging, indicating its diagnostic efficiency.
  • The biomimetic nanoparticles also reduced inflammation markers, highlighting their therapeutic potential in cardiovascular health.
  • This study introduces innovative applications of bionic nanotechnology in both imaging and treatment of atherosclerosis.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68d45b0b31b076d99fa5d2f3https://doi.org/10.58530/2025/0053
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inflammatory-targeted iron oxide nanoparticles contrast agent for magnetic resonance imaging of atherosclerotic plaques2025
  2. 2Exploring atherosclerosis imaging with contrast-enhanced MRI using PEGylated ultrasmall iron oxide nanoparticles2023 · 17 citations
  3. 3Monocyte‐Mimetic Contrast Agent Enables Targeted and Sensitive Magnetic Resonance Imaging of Atherosclerotic Lesions2025 · 4 citations
  4. 4SR-A-Targeted Phase-Transition Nanoparticles for the Detection and Treatment of Atherosclerotic Vulnerable Plaques2019 · 71 citations
  5. 5Iron Oxide Particles for Atheroma Imaging2009 · 137 citations