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September 17, 2025Metabolic Syndrome and Related Disorders

Triglyceride Glucose Index and Related Parameters Are Effective Biomarkers to Identify Metabolic Dysfunction-Associated Steatotic Liver Disease Among Egyptian Adults with Type 2 Diabetes

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Authors

MMMagdy Helmi MegalaaAlexandria UniversityAZAhmed ZeidKafrelsheikh UniversityMZMohamed ZietounAlexandria University

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Overview

Cross-sectional study reveals triglyceride-related parameters effectively diagnose liver disease in type 2 diabetes patients, suggesting a practical diagnostic tool.

Key Points

  • MASLD was diagnosed in 83% of patients with type 2 diabetes, indicating a significant prevalence in this population.
  • TyG-BMI showed the highest predictive accuracy at 0.775, demonstrating its importance as a diagnostic tool for liver disease severity.
  • This cross-sectional study analyzed 600 diabetic adults, with diagnostic methods including FibroScan for hepatic steatosis.
  • The findings support the use of TyG indices as reliable biomarkers for diagnosing and assessing the severity of MASLD.

Cite This Study

Megalaa et al. (2025) studied this question.

synapsesocial.com/papers/68d45b3431b076d99fa5df29https://doi.org/10.1177/15578518251377780
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The relationship between triglyceride-glucose index, triglyceride-glucose-body mass index, and the severity of hepatic steatosis and liver fibrosis in patients with MASLD: a cross-sectional study2026 · 3 citations
  2. 2Triglyceride glucose-body mass index as a practical screening tool for metabolic dysfunction-associated steatotic liver disease in older adults: A community-based cohort study.2026
  3. 3TyG-related indices as reliable markers for identifying MASLD-associated metabolic phenotypes in type 2 diabetes2026
  4. 4Association of triglyceride glucose-body mass index (TyG-BMI) with metabolic dysfunction-associated steatotic liver disease: A systematic review and meta-analysis2025 · 21 citations
  5. 5Triglyceride-glucose-waist circumference index: A powerful tool for metabolic dysfunction-associated steatotic liver disease2025