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September 17, 2025Journal of Drug Design and Medicinal ChemistryOpen Access

Comprehensive Overview of Eugenol: Focusing on Sources, Structure, Pharmacological Activities, Mechanisms of Action, Safety Profile, and Applications

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Authors

AFAhmad FaruqIIIbrahim M. Ibrahim

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Overview

Review of eugenol outlines its pharmacological activities and mechanisms, suggesting micro/nano-formulations may enhance its clinical use.

Key Points

  • Eugenol exhibits a broad spectrum of pharmacological activities, including antioxidant and antimicrobial effects.
  • Bioavailability issues and dose-dependent toxicity limit the clinical potential of eugenol as a therapeutic agent.
  • Advancements in micro/nano-formulations may enhance the effectiveness and safety of eugenol in clinical applications.
  • Understanding the mechanisms of action, such as inhibition of pro-inflammatory enzymes, is crucial for future developments.

Cite This Study

Faruq et al. (2025) studied this question.

synapsesocial.com/papers/68d45e4431b076d99fa5e0f2https://doi.org/10.11648/j.jddmc.20251103.11
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects2025 · 10 citations
  2. 2Spray-Dried Eugenol Microparticles: Physicochemical Characterization and Enhanced Antibacterial Activity2026
  3. 3Inhibitory Effects and Mode of Action of Pure Eugenol Versus Clove Essential Oil on Key Phytopathogenic Fungi2026 · 1 citations
  4. 4Eugenol extraction and characterization from clove as a potential anticancer therapeutic agent against breast cancer: Combining an in vitro and in silico molecular docking and dynamics studies2026
  5. 5Evaluation of antimicrobial and immunomodulatory activities of Eugenol isolated from Syzygium aromaticum in a rat model2025