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September 17, 2025ChildrenOpen Access

A Cross-Sectional Study of Salivary Cortisol, Alpha Amylase, and Measures of Psychological Distress in Children Undergoing Dental Procedures

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Authors

SMShelby MainSSStephen SuchyMCMarcela Rocha de Oliveira Carrilho

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Overview

Cross-sectional study evaluates salivary cortisol and alpha amylase in children, showing limited correlations with psychological distress.

Key Points

  • Psychological distress was reported by 85.3% of participants, indicating high stress levels during dental visits.
  • Cortisol values were outside the normal range for 72.2% of participants, suggesting stress response variability.
  • Correlations between dental anxiety and heart rate showed statistically significant links, indicating heightened physiological responses.
  • Cortisol and alpha amylase levels did not correlate with psychological measures, highlighting potential limitations in these biomarkers.

Cite This Study

Main et al. (2025) studied this question.

synapsesocial.com/papers/68d45e4431b076d99fa5e29ahttps://doi.org/10.3390/children12091235
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of salivary alpha-amylase and cortisol levels in patients undergoing orthodontic mini-implant treatment: a short-term prospective comparative study2025
  2. 2Study of Emotional and Personality Characteristics and Salivary Cortisol Levels in Patients with Unjustified Complaints about Aesthetic Treatment Outcomes in Dentistry2025
  3. 3The Relationship between State Anxiety Scale and Physiological Stress Markers before Dental Procedures: A Cross-sectional Analytical Study of Blood Pressure, Pulse Rate, Oxygen Saturation, and Salivary Amylase Activity2026
  4. 4Comparison of Salivary Stress Biomarkers in Patients with and without Periodontal Diseases: A Cross-sectional Study.2026
  5. 5Comparison of Anxiety Levels with Salivary Cortisol Levels in Patients Undergoing Endodontic and Restorative Treatment2025