Observational analysis showed significant reductions in parasitemia and increased survival time in mice, suggesting Vernonia Amygdalina may help combat malaria effectively.
Key Points
Vernonia amygdalina leaf extract at 600 mg/kg significantly suppressed parasitemia by 60.78% and improved mean survival time.
The stem-bark extract provided similar results, with a 60.62% suppression of parasitemia and a noticeable increase in survival time.
Prophylactic treatment with leaf extract at 200 mg/kg achieved an impressive 91.67% reduction in parasitemia, indicating high efficacy.
These findings suggest Vernonia amygdalina extracts could be a valuable alternative in malaria treatment, especially against artemisinin resistance.