A ratiometric fluorescent probe with dual red/near-infrared emissions for monitoring lysosomal pH fluctuations

Q: What type of study is this?

This is a Experimental Study study.

Huiying Mu; Ryou Tanaka; Ryo Kubota; Koji Miki; Kouichi Ohe

doi:10.1039/d5tb01801c

January 1, 2025Journal of Materials Chemistry B

A ratiometric fluorescent probe with dual red/near-infrared emissions for monitoring lysosomal pH fluctuations

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Key Points

Ratiometric fluorescent probes are effective for detecting pH fluctuations crucial for cellular processes.
The dual red/near-infrared emissions enhance the sensitivity and accuracy of lysosomal pH measurements.
Monitoring lysosomal pH can provide insights into cellular metabolism and its disturbances.
These probes may reveal significant implications for understanding various physiological disorders.

Implication

Ratiometric fluorescent probes showed lysosomal pH changes in cells, indicating their potential for assessing metabolism disorders.

Abstract

Lysosomal pH is a crucial intracellular parameter for evaluating cellular metabolism, as even minor fluctuations are closely associated with various physiological disorders. Ratiometric fluorescent probes have been developed for monitoring...

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Cite This Study

Mu et al. (2025) studied this question.

synapsesocial.com/papers/68d45e6231b076d99fa5ee5b https://doi.org/10.1039/d5tb01801c

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A ratiometric fluorescent probe with dual red/near-infrared emissions for monitoring lysosomal pH fluctuations

Key Points

Implication

Abstract

Discussion

Cite This Study

A ratiometric fluorescent probe with dual red/near-infrared emissions for monitoring lysosomal pH fluctuations

Key Points

Implication

Abstract

Discussion

Cite This Study

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