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September 17, 2025Journal of Community Hospital Internal Medicine PerspectivesOpen Access

Methotrexate Toxicity Management in Polymyalgia Rheumatica: A Case Report

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Authors

DKDevi Meghana KotharuMNR Medical College and Hospital SVSai Diksha VutukuruMNR Medical College and Hospital PPPoulam M. PatelNottingham University Hospitals NHS Trust

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Implication

Case report details methotrexate toxicity and adverse effects in a 68-year-old male with polymyalgia rheumatica, highlighting treatment interventions.

Key Points

Methotrexate treatment led to pancytopenia in a patient with polymyalgia rheumatica, indicating serious toxicity.
A 68-year-old male displayed oral mucosal lesions and reduced oral intake due to methotrexate toxicity signs.
Prompt intervention with folinic acid and filgrastim helped manage the adverse effects of methotrexate toxicity.
Regular monitoring for methotrexate toxicity is crucial for safe management in autoimmune disorders.

Cite This Study

Kotharu et al. (2025) studied this question.

synapsesocial.com/papers/68d4604731b076d99fa5f6ac https://doi.org/10.55729/2000-9666.1531

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Implication

Case report details methotrexate toxicity and adverse effects in a 68-year-old male with polymyalgia rheumatica, highlighting treatment interventions.

Methotrexate Toxicity Management in Polymyalgia Rheumatica: A Case Report

Discussion

Member takes

Implication

Key Points

Cite This Study

Methotrexate Toxicity Management in Polymyalgia Rheumatica: A Case Report

Discussion

Member takes

Implication

Key Points

Cite This Study

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