Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 18, 2025Turkish Journal of BiochemistryOpen Access

miR-30c-5p serves a diagnostic biomarker in chronic heart failure patients and its regulatory role in vascular endothelial

View Full Paper
Ask AI
Bookmark
Share

Authors

DXDan XiongYMYi MeiYZYao Zhu

Discussion

Loading...

Member takes

Overview

Analysis of miR-30c-5p reveals its diagnostic potential in chronic heart failure, highlighting its effect on vascular endothelial cells.

Key Points

  • Reduced serum miR-30c-5p levels can indicate chronic heart failure severity and diagnosis.
  • The ROC curve showed high sensitivity of 83.19% and specificity of 84.69% for miR-30c-5p as a CHF biomarker.
  • In vitro analyses showed that miR-30c-5p mimics promoted HUVECs proliferation and migration while suppressing apoptosis.
  • Logistic regression identified miR-30c-5p as a significant risk factor correlated negatively with BNP and positively with LVEF.

Cite This Study

Xiong et al. (2025) studied this question.

synapsesocial.com/papers/68d463e931b076d99fa63448https://doi.org/10.1515/tjb-2025-0033
View Full Paper
Ask AI
Bookmark
Share