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September 19, 2025Open Access

Clinical and Comorbidity Profile of Metabolic Dysfunction-Associated Fatty Liver Disease: A Retrospective Cohort Study

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Authors

NSNebyu Yonas ShankaCPChavdar S PavlovTTTaisiia Turankova

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Overview

Retrospective cohort study reveals higher prevalence of type 2 diabetes and dyslipidemia in MAFLD patients, indicating a need for integrated management strategies.

Key Points

  • MAFLD patients showed significantly higher BMI and elevated liver enzymes compared to non-MAFLD individuals, highlighting the disease's impact.
  • Type 2 diabetes prevalence was notably higher in MAFLD patients at 49.3%, suggesting strong associations between MAFLD and metabolic disorders.
  • The study employed a retrospective cohort design with 850 adults to assess the clinical and comorbidity profile of MAFLD versus non-MAFLD.
  • Findings emphasize the importance of comprehensive metabolic screening in MAFLD patients, given the associated high comorbidity burden.

Cite This Study

Shanka et al. (2025) studied this question.

synapsesocial.com/papers/68d464e031b076d99fa63b29https://doi.org/10.20944/preprints202509.1210.v1
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Also Consider

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  1. 1Comparison of Clinical Characteristics and Outcomes of MAFLD and NAFLD in Chinese Health Examination Populations2023 · 9 citations
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  4. 4Gastrointestinal functional disturbances in patients with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): a cross-sectional study2026
  5. 5Dietary patterns in the progression of metabolic dysfunction-associated fatty liver disease to advanced liver disease: a prospective cohort study2024 · 22 citations