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This is a Literature Review study.

Multitarget Antimicrobial Mechanisms of Plant Extracts: A Review of Harnessing Phytochemicals Against Drug-Resistant Pathogens

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Review highlights phytochemicals' diverse mechanisms and synergistic interactions in combating antimicrobial resistance.

Phytochemicals disrupt microbial membranes and inhibit enzyme functions, enhancing antimicrobial effects.
The review identifies major classes such as alkaloids and flavonoids, showcasing their therapeutic potential.
Synergistic interactions within extracts improve effectiveness, aiding in overcoming challenges of antimicrobial resistance.
Despite hurdles in standardization and bioavailability, modern technologies can boost the application of phytochemicals.

Al-Arnoot et al. (2025) studied this question.

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