October 10, 2025

Potential of Plant-Derived Phytochemicals in Combating Antimicrobial Resistance: A Comprehensive Review

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This review identifies plant-derived phytochemicals' effects on antimicrobial resistance, highlighting their mechanisms and clinical potential.

Plant-derived phytochemicals inhibit microbial resistance mechanisms, enhancing the effectiveness of antibiotics.
Phytochemicals often target efflux pumps and disrupt microbial membranes, showcasing a spectrum of antimicrobial activity.
This narrative review covered studies from various databases, emphasizing the diversity of phytochemicals' effects.
Translational challenges remain significant for using phytochemicals as alternatives to conventional antibiotics.

Rafeeq et al. (2025) studied this question.

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This review identifies plant-derived phytochemicals' effects on antimicrobial resistance, highlighting their mechanisms and clinical potential.