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September 19, 2025CancersOpen Access

Prevalence and Clinical Significance of Potential Drug–Drug Interactions in Hospitalized Pediatric Oncology Patients: A Prospective Pharmacoepidemiologic Study

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Authors

OZOmid Reza ZekavatNZNarjes ZarsanjMSMohammadamin Sadeghdoust

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Overview

Prospective analysis assessed drug-drug interactions in hospitalized pediatric oncology patients, indicating significant clinical concerns.

Key Points

  • At least 21.2% of pediatric oncology patients experienced documented drug-drug interactions in the study.
  • A total of 197 potential drug-drug interactions were identified, with methotrexate accounting for 156 interactions.
  • The study applied a dual-database screening to enhance detection of potential drug-drug interactions.
  • Clinical teams are encouraged to review medication profiles regularly to mitigate risks from drug-drug interactions.

Cite This Study

Zekavat et al. (2025) studied this question.

synapsesocial.com/papers/68d464ff31b076d99fa64b32https://doi.org/10.3390/cancers17183054
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