Analysis reveals high sensitivity biomarkers in acute myocardial infarction patients, suggesting diagnostic potential.
Background: Acute myocardial infarction (AMI) is a major cause of morbidity and death globally, resulting from a coronary artery blockage, changes in lipid profiles, and a pattern of myocardial infraction that monitors and confirms the early diagnosis of cardiovascular disease using a troponin marker. Objectives: The objectives of this study to assess the diagnostic and prognostic value of hs-CRP, troponin I, and lipid profile in AMI patients in Hawija City. Subjects and Methods: Fifty patients with an acute myocardial infarction and fifty healthy controls participated in the current investigation. An instrument contained the whole clinical profile, demographic information, and medical history of each patient. The High Sensitivity C-Reactive, troponin I, and lipid profiles of an acute myocardial infarction patients at Hawija City, all AMI patients were monitored for the first 24 hours after the onset of symptoms. The Results: The results show that the ratio of male to female in the study and control groups represents 56:0 and 44.0 respectively while the ratio of male to female in control group represents 50.0 in both groups. Furthermore, the outcome demonstrates that the comparison of hs-CRP levels between patients with AMI and the control group, as well as the mean and standard deviation in the study group is 7.44±1.24 and in the control group is 1.7919±0.52. The results also show that the lipid profile was higher in the study group compared to the control group, and the hs-CRP and lipid profile contrast in various early onset and late onset AMI and appear increase of hs-CRP and lipid profile in late onset of AMI 15.55±4.4 comparison in early AMI4.91±0.23. Conclusions: The study concluded that there are alterations in lipid profile and inflammatory marker in AMI cases. The results also reveal that the lipid profile increases in patients with AMI (study group) in a comparison with control group. The results find that the hs-CRP and lipid profile were high in the late AMI in a comparison with an early onset of AMI.
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Kumait et al. (2025) studied this question.
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