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September 21, 2025Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512)Open Access

Preparation and Evaluation of Voriconazole as Topical Organogel

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Authors

HFHiba Muneer FysalHKHanan Jalal Kassab

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Overview

This study demonstrates the effectiveness of a voriconazole organogel, enhancing drug delivery in topical antifungal applications.

Key Points

  • Voriconazole organogel formulations exhibited acceptable physical properties and drug release profiles.
  • The formulation with palmitic acid and grape-seed oil showed superior sustained release of voriconazole.
  • Gelator concentrations were optimized, with studies conducted on viscosity, pH, and drug release.
  • Compatibility analysis confirmed that voriconazole and excipients did not significantly interact.

Cite This Study

Fysal et al. (2025) studied this question.

synapsesocial.com/papers/68d46abb31b076d99fa680adhttps://doi.org/10.31351/vol34iss3pp237-248
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Formulation and evaluation of voriconazole loaded ophthalmic in situ gel using a natural polymer2024
  2. 2Formulation Studies on Microemulsion-Based Polymer Gels Loaded with Voriconazole for the Treatment of Skin Mycoses2025
  3. 3Formulation and Evaluation of Cubosomal In-Situ Gel for Topical Aaplication2025 · 1 citations
  4. 4Formulation and Evaluation of Voriconazole Emulgel2025
  5. 5Design and In Vitro Assessment of Itraconazole Topical Gel for Fungal Infections2025