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This is a Experimental Study study.

Visible-Light-Induced Multifunctionalization Reaction of o-Alkenyl Aromatic Isocyanides, Sulfur Ylide, and Fluorinated Alcohols: Direct Synthesis of 3-Fluoroalkyl-Substituted Indoles

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This multicomponent reaction synthesizes fluorinated indoles from isocyanides and alcohols, suggesting efficient bond formation.

The reaction efficiently constructs fluorinated indole derivatives in a single step using available precursors.
It forms two C–O and two C–C bonds simultaneously, enhancing synthetic efficiency and potential applications.
Applications include synthesizing complex indoles and carbazole structures, showcasing versatility in organic synthesis.
This approach employs visible-light to activate the reaction, making it a greener method for indole synthesis.

Gong et al. (2025) studied this question.

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