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September 19, 2025BiomoleculesOpen Access

Exploring the Inhibitory Potential of Six Porphyrin Compounds Against α-Amylase and α-Glucosidase Linked to Diabetes

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Authors

SZShuo ZhangZLZi LiuQMQiang Ma

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Overview

Investigating the role of six porphyrin compounds in inhibiting α-amylase and α-glucosidase, suggesting new diabetes therapies.

Key Points

  • Six porphyrin compounds significantly inhibited both α-amylase and α-glucosidase activities.
  • The inhibitory potency against α-amylase ranged from 13.03 to 245.04 μg/mL, showing variable effectiveness among compounds.
  • Fluorescence quenching experiments indicated that the compounds formed complexes with enzymes, altering their activity.
  • The research provides a basis for developing new therapeutic strategies in diabetes management.

Cite This Study

Zhang et al. (2025) studied this question.

synapsesocial.com/papers/68d46cd731b076d99fa6930bhttps://doi.org/10.3390/biom15091338
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