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This is a Quantitative Study study.

September 23, 2025Human Brain MappingOpen Access

The Impact of Early Life Exposure to Air Pollution on the Brain: A Diffusion MRI Study in 10–13‐Year‐Old Children With and Without ADHD Diagnosis

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Diffusion MRI study assesses air pollution's effects on brain metrics in children, indicating outcomes for ADHD and typical development.

Lower global fractional anisotropy and higher mean diffusivity were linked to early life nitrogen dioxide exposure.
Among the 425 children analyzed, no significant fixel-level associations were observed despite the large sample size.
Children diagnosed with ADHD did not show increased sensitivity to the adverse effects of air pollution.
Findings imply that diffusion MRI measures are crucial indicators of brain health in relation to air pollution exposure.

Lewandowska et al. (2025) studied this question.

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