September 23, 2025Open Access

Temporal trends in hypertension and pulmonary embolism–related mortality in the United States: A population-based study using CDC WONDER, 2000–2020

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Hypertension and pulmonary embolism-related mortality rose significantly from 2000 to 2020, indicating a worrying trend in public health.
The age-adjusted mortality rate (AAMR) increased from 1.3 to 3.6 per 100,000, with an average annual percent change (AAPC) of 4.5%, highlighting a growing concern.
A retrospective analysis using CDC WONDER data provided insights into demographic and geographic disparities in mortality trends.
Findings signal a pressing need for targeted public health interventions to address the rising mortality rates and associated disparities.

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Retrospective analysis reveals rising hypertension and pulmonary embolism mortality, indicating disparities across demographics and geography.

Sajjad et al. (2025) studied this question.

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Retrospective analysis reveals rising hypertension and pulmonary embolism mortality, indicating disparities across demographics and geography.