Visible-Light-Driven Cascade Cyclization: A Modular Approach to Functionalized 4-Pyrrolin-2-ones

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This is a Experimental Study study.

Rupashri Dash; Karan Ramdas Thombare; Anindya Sundar Das; Sandip Murarka

doi:10.1039/d5cc04703j

January 1, 2025Chemical Communications

Visible-Light-Driven Cascade Cyclization: A Modular Approach to Functionalized 4-Pyrrolin-2-ones

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Key Points

The method effectively produces densely functionalized 4-pyrrolin-2-ones using visible-light-driven reactions.
Utilizing Ru(II) photocatalysis allows for efficient radical cascade cyclization with diverse products.
The modular approach supports the creation of benzylated compounds, enhancing synthetic versatility.
This research highlights a promising strategy for synthesizing complex molecules from simple precursors.

Implication

Cascade cyclization enables efficient synthesis of diverse 4-pyrrolin-2-ones, suggesting new applications.

Abstract

We report an efficient and modular strategy for the construction of densely functionalized 4-pyrrolin-2-ones via visible-light-driven Ru(II) photocatalysis. The radical cascade cyclization approach enables the diversity-oriented synthesis of benzylated and...

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Cite This Study

Dash et al. (2025) studied this question.

synapsesocial.com/papers/68d6d8ba8b2b6861e4c3f04c https://doi.org/10.1039/d5cc04703j

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Visible-Light-Driven Cascade Cyclization: A Modular Approach to Functionalized 4-Pyrrolin-2-ones

Key Points

Implication

Abstract

Discussion

Cite This Study

Visible-Light-Driven Cascade Cyclization: A Modular Approach to Functionalized 4-Pyrrolin-2-ones

Key Points

Implication

Abstract

Discussion

Cite This Study

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