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This is a Cohort Study study (also classified as: Experimental Study).

Optimize bioavailability of silyamrin nanoparticles using Eudragit-pluronic F-68 combination

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The optimized silymarin nanoparticles demonstrated a mean diameter of 114.4 to 136.7 nm, indicating successful formulation.
Zeta potential values confirmed stability in the nanoparticle suspension, enhancing product reliability and efficacy.
In vitro studies revealed sustained drug release behavior consistent with the Peppas equation, supporting controlled release over a duration of one day.
Stability tests at 4°C showed that refrigerated storage is optimal for maintaining the integrity of the nanoparticles.

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This research investigates the formulation of silymarin nanoparticles using Eudragit and Pluronic F-68, showing improved drug release and stability.

Kotame et al. (2025) studied this question.

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This research investigates the formulation of silymarin nanoparticles using Eudragit and Pluronic F-68, showing improved drug release and stability.