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September 28, 2025MedicinaOpen Access

Impact of Surgical Approach, Patient Risk Factors, and Diverting Ileostomy on Anastomotic Leakage and Outcomes After Rectal Cancer Resection: A 5-Year Single-Center Study

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Authors

DNDeividas NekrosiusLithuanian University of Health SciencesEGEdvinas GvozdasLithuanian University of Health SciencesGPGabriele Marija PratkuteLithuanian University of Health Sciences

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Overview

Retrospective cohort study shows that surgical approach and patient risk factors impact anastomotic leakage, suggesting diverting ileostomy improves outcomes.

Key Points

  • Anastomotic leakage occurred in 20.5% of laparoscopic patients and 18.4% of open patients, showing similar rates between approaches.
  • Reoperation rates were higher in laparoscopic surgery (13.1%) compared to open surgery (6.7%), indicating potential complications.
  • Patients with higher ASA scores and older age were identified as independent risk factors for anastomotic leakage, emphasizing the need for careful patient assessment.
  • The use of a diverting ileostomy significantly reduced the risk of anastomotic leakage, suggesting its broader application in high-risk patients.

Cite This Study

Nekrosius et al. (2025) studied this question.

synapsesocial.com/papers/68d9052941e1c178a14f586ahttps://doi.org/10.3390/medicina61101751
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Risk Factors for Anastomotic Leak in Patients Undergoing Surgery for Rectal Cancer Resection: A Retrospective Analysis2025
  2. 2A nationwide study on anastomotic leakage after colonic cancer surgery2012 · 202 citations
  3. 3Risk Factors for Anastomotic Leakage after Laparoscopic Rectal Resection2010 · 87 citations
  4. 4Assessment of Risk Factors for Anastomotic Leakage After Resection for Rectal Cancers2024
  5. 5Prophylactic defunctioning stomas improve clinical outcomes of anastomotic leak following rectal cancer resections: An analysis of the US Rectal Cancer Consortium2024 · 12 citations