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July 10, 2026BMC SurgeryOpen Access

Efficacy of anastomotic reinforcement suture in laparoscopic anterior resection for middle–low rectal cancer: a propensity-score-matched cohort study

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Authors

BZBinbin ZhengSecond Military Medical UniversityHZHu ZNanjing University of Chinese MedicineDYDejun YangSecond Military Medical University

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Overview

Propensity-score-matched cohort study compares anastomotic reinforcement suture with other measures in reducing leakage after surgery.

Key Points

  • This study aims to evaluate the effectiveness of various preventive measures against anastomotic leakage after laparoscopic anterior resection for rectal cancer.
  • Retrospective review of consecutive patients undergoing laparoscopic anterior resection.
  • Patients were divided into four groups based on prophylactic measures: LARS, TDT, diverting ileostomy, and no prophylaxis.
  • Propensity score matching using multinomial logistic regression to ensure comparability across groups.
  • Overall anastomotic leakage rates were significantly lower in the LARS group at 2.5% compared to 15.0% in the no prophylaxis group (P < 0.05).
  • No patients in the LARS and diverting ileostomy groups required reoperation for severe leakage, while 6.3% and 10.0% did in the TDT and no prophylaxis groups, respectively (P < 0.05).
  • Stoma-related complications occurred in 20.0% of patients with diverting ileostomy, with no such complications in the other groups.

Cite This Study

Zheng et al. (2026) studied this question.

synapsesocial.com/papers/6a508b536eeac72a437a004ahttps://doi.org/10.1186/s12893-026-03984-z
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effectiveness of anastomotic reinforcement sutures in reducing anastomotic leakage risk after laparoscopic rectal cancer surgery: a pooled and integration analysis2024 · 3 citations
  2. 2Impact of Surgical Approach, Patient Risk Factors, and Diverting Ileostomy on Anastomotic Leakage and Outcomes After Rectal Cancer Resection: A 5-Year Single-Center Study2025 · 6 citations
  3. 3Prophylactic defunctioning stomas improve clinical outcomes of anastomotic leak following rectal cancer resections: An analysis of the US Rectal Cancer Consortium2024 · 12 citations
  4. 4Management of anastomotic leak after elective anterior resection for rectal cancer: A systematic review and pooled analysis2025 · 9 citations
  5. 5Comparison analysis of short-term outcomes between degradable stent placement and diverting ileostomy in mid-to-low rectal cancer: a retrospective cohort study2026