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September 26, 2025Iranian Journal of Allergy Asthma and ImmunologyOpen Access

Immunological Insights into the PI3K-Akt Pathway in Osteoporosis and Periodontitis: A Proteomic and Metabolomic Approach

Jing Qi Yunqing Pang Qian Yang Yibin Wang Diandong Hou Jing Wang

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Key Points

The study highlights the connection between the pi3k-akt pathway and its impact on osteoporosis and periodontitis, suggesting targeted therapeutic approaches.
Using proteomic and metabolomic strategies provided deeper insights into immune responses linked to osteoporosis and periodontitis progresses.
Understanding these mechanisms could lead to innovative treatments for osteoporosis and periodontitis by modifying the pi3k-akt pathway.
The findings emphasize the need for further research on the immunological aspects of osteoporosis and periodontitis related to the pi3k-akt pathway.

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Implication

This research uncovers the PI3K-Akt pathway's role in osteoporosis and periodontitis through proteomic and metabolomic analysis.

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Cite This Study

Qi et al. (2025) studied this question.

synapsesocial.com/papers/68d90a0641e1c178a14f6554 https://doi.org/10.18502/ijaai.v24i5.19753

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Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Research Progress on the Involvement of PI3K-AKT Signaling Pathway in the Pathogenesis of Osteoporosis2024
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5A microbiota–substrate–metabolite–target network suggests AKT1-associated links between gut microbiota-derived metabolites and osteoporosisOriginal Research · 2026