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September 29, 2025Renal Replacement TherapyOpen Access

N-acetylcysteine for treatment of anemia in children with kidney failure: a prospective study

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Authors

HAHeba Mostafa AhmedBeni-Suef UniversityFMFatma Abdel MaksoudCairo UniversityASAhmed R. SayedBeni-Suef University

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Overview

Prospective study shows n-acetylcysteine enhances hemoglobin and cardiac indices in children, implying antioxidant benefits.

Key Points

  • N-acetylcysteine significantly improves hemoglobin levels in children with kidney failure undergoing hemodialysis.
  • Total antioxidant capacity increased and total oxidative stress decreased after 3 months of treatment with NAC.
  • The study assesses cardiac contractility and LV diameters, finding protective cardiovascular effects from NAC.
  • N-acetylcysteine may provide antioxidant protection, enhancing overall health in pediatric kidney failure patients.

Cite This Study

Ahmed et al. (2025) studied this question.

synapsesocial.com/papers/68da58d1c1728099cfd10e27https://doi.org/10.1186/s41100-025-00671-2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1N-Acetylcysteine for Treatment of Anemia in Children with Kidney Failure: A Prospective Study2025
  2. 2Effect of N-Acetylcysteine on Endothelial Dysfunction in Dialysis Patients2007 · 38 citations
  3. 3Impact of NAC on inflammation and nutrition in hemodialysis2025
  4. 4N-Acetylcysteine Improves Arterial Vascular Reactivity in Patients with Chronic Kidney Disease2009 · 18 citations
  5. 5Effects of N-Acetylcysteine on Angiotensin-Converting Enzyme Plasma Activity in Patients with Chronic Kidney Diseases2008 · 2 citations